Welcome to The Official Website of QR 678.
This is the official product website of the QR 678 ® hair growth therapy, which is made in India, which has become very popular globally & is consistently being rated amongst the biggest clinical inventions all over the world.
The QR 678 ®is a proprietary, first in class hair fall & hair regrowth therapy, which has revolutionized the treatment of hair fall in alopecia. This formulation has been named QR678 inspired by the new generation ubiquitous presence of “Quick Response“ QR code. 678 in Morse Code signifies “there is no answer”. This formulation has been named QR678™ to signify a “Quick Response to a disease which earlier had no answer”.
The QR 678 ® was invented by a team lead by Dr. Debraj Shome, a renowned Facial Plastic Surgeon and Dr. Rinky Kapoor, a well-known dermatologist. Dr. Shome & Dr. Kapoor co-founded The Esthetic Clinics®, which are a chain of top class dermatology & plastic surgery centers located in various cities in India.
Dr. Shome & Dr. Kapoor have had accomplished career in clinical research in plastic surgery, cosmetic surgery and aesthetic dermatology. In fact, The Esthetic Clinics ® are India’s first private organization to be approved by Drug Controller General of India (DCGI) & Central Drugs Standard Control Organisation (CDSCO) under Directorate General of Health Services (DGHS), for conducting clinical trials for Plastic Surgery, Cosmetic Surgery & Dermatology, in India.
How does it work?
The QR 678 ® therapy arrests hair fall & increases the thickness, number & density of existing hair follicles, leading to greater coverage in patients with alopecia. Since, the polypeptides used in QR 678 ® are anyways present in scalp full of hair (they get decreased in scalps which have hair fall), it is the enrichment of the scalp skin with these polypeptides which cause hair growth. Since these polypeptides are anyways normally present in the scalp, replenishing the scalp with these is not artificial and does not have any side effects.
Unlike currently available hair fall treatments like minoxidil & finasteride, the QR 678 ® therapy is almost completely devoid of side effects. It is locally administered over the scalp skin by mesotherapy & as such is not absorbed into the systemic circulation. Unlike currently available hair transplant therapies like Follicular Unit Extraction (FUE) & Follicular Unit Transplantation (FUT), the QR 678 ® is non invasive, non surgical & therefore safer & more affordable.
The QR 678 ®therapy works very well in androgenetic alopecia or male pattern baldness & female pattern hair loss. The QR 678 ® therapy has also demonstrated encouraging results in post chemotherapy induced hair loss, treatment of hair conditions like seborrheic dermatitis & in immunogenic diseases like alopecia areata.
How was it invented & Invention Timelines:
In 2006, While working on a drug for ocular & neural cancers, Dr. Shome stumbled upon potential causes of hair fall, in the animal trial he was pursuing.
This research on Retinoblastoma conducted in collaboration with the Indian Institute of Technology, Mumbai, India (IIT) threw up an interesting phenomenon of hair loss in the animal model.
From 2006-2008, Determined pursuit of this insight leads to identification of growth factors and polypeptides possibly influencing hair growth. Signal transduction of proteins, based on animal models, were used to identify 5 naturally occurring growth factors/ polypeptides in humans.
In 2009, the First in Human trial commenced to study dose ranging and evolve optimum concentration mix to yield the best in class results.
The QR 678 ® hair formulation therapy was featured on Times Of India (India’s largest read English news daily), on first page, all editions on September 19th, 2010.
Subsequently, from 2013-2016, a Phase III clinical user trial in a large cohort of 1000 patients of both genders was completed, to test efficacy & safety of the proposed formulation. This clinical trial was published in a very reputed, top, American Journal, Journal of Cosmetic & Laser Therapy, in 2017. After 8 sessions, global photographs showed improvement from baseline for 71% patients, a decreased score for 10% patients, & no change in score for 19% patients. The findings of this study suggest that the beneficial clinical effects of this QR 678 ® hair formulation therapy are similar in men & women, across different age groups, & in patients irrespective of the presence of metabolic disorders like diabetes, hypertension, hypercholesterolemia etc.
A composition & mechanism of administration patent was awarded to the QR 678 ® hair formulation on 11th July 2017, by the United Stated Patent & Trademark Office (USPTO) – USA patent no 9, 700, 504 B2. Details of the patent are available below:
The Indian Patent Application was granted a composition and method of administration comprehensive patent, vide Indian Patent No. IN310925, granted on 5th April, 2019. Details of the patent are available here:
The Indian FDA gave an approval for commercial manufacturing & sale in March 2019.
The QR678 Storyline
Serendipity has been the driving force behind this invention. Much like Viagra, research into Retinoblastoma (a form of ocular cancer) brought out the side effects into focus, culminating into the formulation today known as QR 678 ®