The QR678® Neo

is a proprietary, first in class hair fall & hair regrowth therapy, which has revolutionized the treatment of hair fall in alopecia. This formulation has been named QR678® Neo inspired by the new generation ubiquitous presence of “Quick Response“ QR code. 678 in Morse Code signifies “there is no answer”. This formulation has been named QR678™ to signify a “Quick Response to a disease which earlier had no answer”. The QR678® Neo was invented by a team led by Dr. Debraj Shome, a renowned Facial Plastic Surgeon and Dr. Rinky Kapoor, a well-known dermatologist.Dr. Shome & Dr. Kapoor have had accomplished career in clinical research in plastic surgery, cosmetic surgery and aesthetic dermatology.

Composition of QR678® Neo Hair Regrowth Formulation:

The effects of the active ingredients of QR678® Neo on the scalp skin are as follows:

S.No. 1 Sh-Polypeptide-9 (bio-mimicking VEGF)
Function:

Sh-Polypeptide-9 is essential for angiogenesis and vascular permeability, may be responsible for maintaining proper vasculature around the hair follicle during the anagen growth phase. The highest expression of this peptide is found in Dermal papilla cells, and, is also expressed by follicular keratinocytes of the outer root sheath.
It has been found to stimulate hair growth and increase hair size through facilitation of nutrient feeding to hair follicle by inducing angiogenesis (Ref. Kiichiro Y. et al., 2001, J. Clin. Invest. 107: 409–417).

S.No. 2 Sh-Polypeptide-1 (bio-mimicking bFGF)

Sh-Polypeptide-1 has ability to stimulate neovascularization, is a potent in vitro mitogen for capillary endothelial cells, and stimulates angiogenesis in vivo
This peptide may regulate the mitotic activity of epithelial-derived cells
It is found in the Outer Root Sheath and in the region of the basal lamina of the follicle bulb, suggesting a role in bulb proliferation and fiber growth.
It affects hair follicle initiation and development.

S.No. 3 Sh- Oligopeptide-2 (bio-mimicking IGF-1)

Sh- Oligopeptide-2 appears to sustain normal anagen growth. They facilitate follicular proliferation, tissue remodeling, and the hair growth cycle, as well as follicular differentiation. IGF-1 mediated signaling is an important mitogenic and morphogenetic regulator in hair follicle biology.
Androgen induction of follicular epithelial cell growth is mediated via this biomimetic peptide from dermal papilla cells.
Strengthen hair while stimulating hair follicles to produce strong hair shaft.

S.No. 4 Sh-Polypeptide-3 (bio-mimicking KGF)

Sh-Polypeptide-3 has been shown to regulate proliferation and differentiation in epithelial tissues and may regulate the clonogenic cells (stem cells) of the hair follicle.
It increases hair follicle survival following cytotoxic insult.
It stimulates capillary endothelial cell migration and proliferation and thus causes neovascularization. (Journal of Cell Science 112, 2049-2057 (1999)).
It helps strengthen hair while stimulating hair follicles to produce strong hair shaft.

S.No. 5 Sh-Oligopeptide-4 (bio-mimicking Thymosin β4)

Important mediator of cell migration and differentiation, it also promotes angiogenesis.
Thymosin β4 accelerates hair growth, in part, due to its effect on critical events in the active phase of the hair follicle cycle, including promoting the migration of stem cells and their immediate progeny to the base of the follicle, differentiation, and extracellular matrix remodeling.
Hepatocyte growth factor up-regulates thymosin β4 expression and may be acting by increasing thymosin β4 and/or synergizing with it

S.No. 6 Copper tripeptide-1

Delivery of copper peptide to the base of follicles helps strengthen hair while stimulating hair follicles to

produce strong hair shaft.

Increase follicle size.
Rebuilds the blood supply to damaged follicles, elevates the production of vascular endothelial growth factor.
Increases melanin synthesis, necessary to keep hair from turning grey.
Increases subcutaneous fat below the scalp which seems to support function for the hair follicle.
Prolongs the hair growth phase.
Inhibits 5-alpha reductase, the enzyme that reduces testosterone to DHT. DHT, in turn, is responsible for androgenetic alopecia. (Ref. H Uno. et al. 1995. Journal of Invest. Dermatology. 101: 143-147) inhibit the forma tion of DHT, hence reducing hair loss from male pattern balding in both men and women.
Reduces inflammation.

S.No. 7 Ascorbic acid

Function: Vitamin C helps build collagen, which is highly important for hair growth, as well as maintaining the strength of hair. Vitamin C plays a necessary role in absorbing iron, which keeps the hair strands strong and healthy.

S.No. 8 Niacinamide

Function: Improves the scalp skin barrier function so that the hair follicles can develop properly.

S.No. 9 Retinol

Function: The follicle disintegrates during catagen in normal process. However, in case of alopecia, the hair follicle stem cell population remains, but the hair follicle dermal papilla detaches from the stem cells and prevents mesenchymal–epithelial interactions necessary for hair follicle cycling. This is particularly accentuated in Vitamin-A deficiency. Therefore Retinol administration is seen to help.

S.No. 10 Pantothenic acid

Function: Maintaining proper levels of pantothenic acid can strengthen hair follicles and their cells. This vitamin contributes to the nourishment of hair follicles, helping them to function properly and promote the growth of hair. Pantothenic acid can also help relieve the skin itching and flaking associated with dandruff and other similar disorders.

How does it work?

The QR678® Neo therapy arrests hair fall & increases the thickness, number & density of existing hair follicles, leading to greater coverage in patients with alopecia. Since, the polypeptides used in QR678® Neo are anyways present in scalp full of hair (they get decreased in scalps which have hair fall), it is the enrichment of the scalp skin with these polypeptides which cause hair growth. Since these polypeptides are anyways normally present in the scalp, replenishing the scalp with these is not artificial and does not have any side effects.
Unlike currently available hair fall treatments like minoxidil & finasteride, the QR678® Neo therapy is almost completely devoid of side effects. It is locally administered over the scalp skin by mesotherapy & as such is not absorbed into the systemic circulation. Unlike currently available hair transplant therapies like Follicular Unit Extraction (FUE) & Follicular Unit Transplantation (FUT), the QR678® Neo is non invasive, non surgical & therefore safer & more affordable. The QR678® Neo therapy works very well in androgenetic alopecia or male pattern baldness & female pattern hair loss. The QR678® Neo therapy has also demonstrated encouraging results in post chemotherapy induced hair loss, treatment of hair conditions like seborrheic dermatitis & in immunogenic diseases like alopecia areata.

Intellectual Property & Timelines:

The QR678® Neo storyline Serendipity has been the driving force behind this invention. Research into Retinoblastoma (a form of ocular cancer) brought out the side effects into focus, culminating into the formulation today known as QR678® Neo
Here is a link to more information on mechanism of administration of the QR678® Neo therapy:

QR678 NEO: NATURAL INGREDIENTS
BACKED BY SCIENCE

The QR678® Neo therapy is a proprietary, first-in-class therapy, backed by science that arrests hair fall & increases the thickness, number, and density of existing hair follicles leading to greater coverage in hair loss. The biomimetic polypeptides used in the formulation mimic the action of specific human hair growth related growth factors that are naturally present in our scalp, making it natural growth factor-based treatment. The polypeptides penetrate deep into the scalp and provide nourishment to the scalp, which results in hair growth. Unlike other treatments that contains minoxidil & finasteride, QR678® Neo therapy is completely devoid of side effects.

HOW DOES IT WORK?

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Benefits of choosing QR678® Neo

QR678® Neo ADVANTAGES

QR678 Advantages 04-min
No side Effects
(Derived From Plants)
QR678 Advantages 06-min

Quick & Effective (Single
Session in 10 Minutes)

QR678 ADVANTAGES ICON (6)
Patented and Regulatory Approved in Multiple Geographies
QR678 ADVANTAGES ICON (7)
QR678 Advantages 05-min

Non Surgical

QR678 Advantages 07-min
About 90%
Success Rate
QR678 ADVANTAGES ICON (3)

13+ Published Researched Clinical Trials Demonstrating Efficacy

LIFE CHANGING RESULTS

PRE TREATMENT

POST 6 SESSIONS

PRE TREATMENT

POST 6 SESSIONS

49 year old female was suffering from post chemotherapy induced hair loss. She achieved impressive results with QR678®, a completely plant derived formulation.

39 year old male suffering from male pattern hair loss for 15 years gained a significant amount of hair with QR678®

PRE TREATMENT

POST 6 SESSIONS

25 year old female from alopecia areata, was also diagnosed with hypothyroid. She achieved impressive results with QR678, a completely steroid-off treatment.

PRE TREATMENT

POST 6 SESSIONS

39 year old male suffering from male pattern hair loss for 15 years gained a significant amount of hair with QR678

MEDIA INTERVIEWS

TESTIMONIALS

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Testimonial #1 Designation

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Testimonial #1 Designation

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    HIGHLIGHTS IN MEDICAL CONFERENCES

    CUTICON – December 2023

    Dazzling moments at Cuticon 2023, Gujarat! QR678 Neo took centre stage, earning accolades from top medical professionals.
    FADS – October 2023
    QR678 Neo made it’s presence felt at FADS (Face Aesthetics Dermatologists Society), the 7th International Conference held at Goa. Renowned dermatologists got QR678 Neo administered and shared their positive experience.
    CDCON – September 2022
    QR678® Neo drew attention with an enlightening session and live demonstration at CDCON 2022 – a platform to challenge changing practices along the lines of Exploration and Innovation.

    GLOBAL PRESENCE

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    FAQ'S

    QR678® Neo is a mixture of natural growth factors that are already present in the scalp and therefore it is completely safe to use on everybody. It has the right concentration of specific hair growth factors and QR678® Neo does not have any side effects, is performed as an outpatient procedure and the results are visible within eight weeks of starting the treatment. You can listen for yourself what the patients say about QR678® Neo hair fall treatment https://www.youtube.com/watch?v=pIvjpQgSsrc

    QR678® Neo injections are administered in 8-12 sessions in about 3-4 weeks apart. The results are visible after few weeks. Once you have achieved the desired results the injections need not be repeated unless the hair fall starts again. This is because QR678® Neo make the hair follicles healthy. Get to know more about why QR678® Neo is highly effective in treating hair fall and increasing hair growth. http://www.qr678.in/

    QR678® Neo is a completely safe treatment without side effects and you can go about your daily routine after the sessions. The only care you need to take is to use a gentle shampoo not before the next day of the treatment and avoid scratching and rubbing the treating area. If you have any other problem then consult your dermatologist. https://www.youtube.com/watch?v=LNm2z3EGLxg

    Yes, using QR678® Neo after hair transplant produces very successful results. QR678® Neo gives faster density and reduces the catagen loss of transplanted hair. The growth factors in QR678® Neo help in faster healing and activate the dormant follicles and thus - Increase the viability of hair follicles - Improve healing and repairing of tissue process - Strengthen the inactive hair follicles and stimulate hair growth - Improves the health of existing hair and they will become fuller and stronger QR678® Neo can be given in multiple treatment sessions after three to four weeks after successful hair transplant surgery. QR678® Neo can also be used before the hair transplant surgery to reduce the area of transplant and  improve the results.

    QR678® Neo is a relatively new treatment for hair fall and hair regrowth but in the short time of its invention QR678® Neo has proven to be more effective than PRP and stem cell treatment for reducing hair fall. QR678® Neo produces longer lasting and better results and is completely safe and without any side effects. QR678® Neo can help treat and rogenetic alopecia, female pattern hair loss, and hair loss because of chemotherapy, seborrheic dermatitis, and alopecia areata. PRP and stem cell on the other hand do not have the specific concentration of required growth factors, they lack standardisation in terms of treatment protocols and preparation of the solution injected and lack good quality studies to prove their benefits. produce guaranteed results and can cause tightness and tenderness in scalp, scar tissue formation, calcification of the injected points, and formation of scar tissues. Both processes are still under investigation and their results are still awaiting confirmation. Dr Rinky Kapoor of The Esthetic Clinics explains the difference between QR678® Neo and stem cell here: https://www.youtube.com/watch?v=wgNihm8ciu4 and https://www.youtube.com/watch?v=ZUWXKzVh0PM

    Yes genetic hair loss can be treated if the treatment is started in time. Heredity hair loss usually runs in the family and can affect both men and women. If you too have a close elder relative who lost his or hair in a patterned baldness then you should keep a close eye on your hair too. Hereditary hair loss usually happens in a pattern; M or W shaped in men and along the hair part in women. See the doctor immediately if you suffer from hair loss. There are many common and successful treatments available for genetic hair loss which include

     

    - Topical and oral medications: These include Minoxidil topical lotion and Finasteride tablets.

    - Hair transplantation using FUT and FUE methods.

    - Nutritional supplements: Your physician might also suggest some hair supplements that can help arrest hair fall. Dietary supplements containing Vitamin A, C, and Biotin, zinc, and iron can also help control hair fall caused because of genetics.

    Alopecia post chemotherapy is a very common consequence of cancer treatments and therapies and it is often the most psychologically and socially devastating side effect. Many patients shy away from the treatments because of fear of hair fall and hair loss. However, in most cases, such alopecia is reversible but the recovery takes several months and even up to a year. Some basic latest treatment methods will speed up the healing: - Scalp Cooling: This is a FDA approved method for patients suffering from breast cancer. Scalp cooling or hypothermia results in constriction of the blood vessels in the scalp, which in turn leads to reduced delivery of chemotherapy to the hair. Scalp cooling devices consist of cooling unit that circulate the coolant on the scalp. This is done about 30 minutes before the start of chemotherapy. Patients can feel some mild discomfort, nausea, and dry skin because of scalp cooling. - Topical Minoxidil: Minoxidil helps by increasing the blood flow to the hair follicle thereby preventing miniaturization of hair follicle. - QR678® Neo hair regrowth treatment: QR678® Neo is a FDA approved, completely safe hair regrowth treatment that has no side effects or causes any discomfort to the patient. Clinical trials have proved QR678 to be effective in treatment of chemotherapy induced alopecia in both men and women. The results of QR678® Neo last lifelong.

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